Swallowing a cellular automaton pill: Predicting drug release from a matrix tablet
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چکیده
منابع مشابه
Swallowing a cellular automaton pill: Predicting drug release from a matrix tablet
Matrix tablets are drug delivery devices designed to release a drug in a controlled manner over an extended period of time. We develop a cellular automaton (CA) model for the dissolution and release of a water-soluble drug and excipient from a matrix tablet of water-insoluble polymer. Cells of the CA are occupied by drug, excipient, water or polymer and the CA updating rules simulate the dissol...
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ژورنال
عنوان ژورنال: SIMULATION
سال: 2014
ISSN: 0037-5497,1741-3133
DOI: 10.1177/0037549713516877